XA68_16386 protein (Ophiocordyceps unilateralis)

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

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[Homology]

Score

XA68_16386

Uncharacterized protein. (68 aa)

Predicted Functional Partners:

XA68_10939

0.999

RPS0

0.999

XA68_16913

0.999

XA68_16104

0.999

XA68_16558

0.999

XA68_15946

0.999

XA68_15287

0.999

XA68_14995

0.999

XA68_15417

0.999

XA68_15292

0.999

Your Current Organism:

Ophiocordyceps unilateralis

NCBI taxonomy Id: 268505
Other names: Cordyceps unilateralis, O. unilateralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RPS0	XA68_10939	A0A2A9P4F9	A0A2A9NY03	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	0.999
RPS0	XA68_14995	A0A2A9P4F9	A0A2A9P859	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	S4 RNA-binding domain-containing protein; Belongs to the universal ribosomal protein uS4 family.	0.999
RPS0	XA68_15287	A0A2A9P4F9	A0A2A9P7I1	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Uncharacterized protein.	0.998
RPS0	XA68_15292	A0A2A9P4F9	A0A2A9P8R3	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.999
RPS0	XA68_15417	A0A2A9P4F9	A0A2A9P8F7	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Ribosomal_S10 domain-containing protein.	0.999
RPS0	XA68_15946	A0A2A9P4F9	A0A2A9P753	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Uncharacterized protein.	0.998
RPS0	XA68_16104	A0A2A9P4F9	A0A2A9P5W1	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
RPS0	XA68_16386	A0A2A9P4F9	A0A2A9P6Q3	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Uncharacterized protein.	0.999
RPS0	XA68_16558	A0A2A9P4F9	A0A2A9P623	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Ribosomal_L7Ae domain-containing protein.	0.998
RPS0	XA68_16913	A0A2A9P4F9	A0A2A9P5D2	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	Ribosomal_L7Ae domain-containing protein.	0.999
XA68_10939	RPS0	A0A2A9NY03	A0A2A9P4F9	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.	0.999
XA68_10939	XA68_14995	A0A2A9NY03	A0A2A9P859	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	S4 RNA-binding domain-containing protein; Belongs to the universal ribosomal protein uS4 family.	0.999
XA68_10939	XA68_15287	A0A2A9NY03	A0A2A9P7I1	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.998
XA68_10939	XA68_15292	A0A2A9NY03	A0A2A9P8R3	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family.	0.999
XA68_10939	XA68_15417	A0A2A9NY03	A0A2A9P8F7	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Ribosomal_S10 domain-containing protein.	0.999
XA68_10939	XA68_15946	A0A2A9NY03	A0A2A9P753	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.998
XA68_10939	XA68_16104	A0A2A9NY03	A0A2A9P5W1	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
XA68_10939	XA68_16386	A0A2A9NY03	A0A2A9P6Q3	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Uncharacterized protein.	0.999
XA68_10939	XA68_16558	A0A2A9NY03	A0A2A9P623	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Ribosomal_L7Ae domain-containing protein.	0.999
XA68_10939	XA68_16913	A0A2A9NY03	A0A2A9P5D2	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family.	Ribosomal_L7Ae domain-containing protein.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

50

average node degree:

9.09

avg. local clustering coefficient:

0.889

expected number of edges:

13

PPI enrichment p-value:

3.55e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1901071

Glucosamine-containing compound metabolic process

4 of 58

1.88

1.54

0.00073

GO:0034221

Fungal-type cell wall chitin biosynthetic process

2 of 3

2.87

1.13

0.0092

GO:0006048

UDP-N-acetylglucosamine biosynthetic process

2 of 4

2.74

1.1

0.0103

GO:0006046

N-acetylglucosamine catabolic process

2 of 4

2.74

1.1

0.0103

GO:0006596

Polyamine biosynthetic process

2 of 5

2.64

1.09

0.0103

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0047419

N-acetylgalactosamine-6-phosphate deacetylase activity

2 of 2

3.04

1.19

0.0073

GO:0008448

N-acetylglucosamine-6-phosphate deacetylase activity

2 of 2

3.04

1.19

0.0073

GO:0003824

Catalytic activity

11 of 5072

0.38

0.27

0.0382

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15182

Synthesis of UDP-N-acetyl-glucosamine, and Glucosamine catabolic process

5 of 8

2.84

4.94

5.87e-10

CL:18181

Melatonin metabolic process, and Staurosporine biosynthesis

3 of 5

2.82

2.66

1.34e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00520

Amino sugar and nucleotide sugar metabolism

5 of 153

1.56

1.82

2.37e-05

map01100

Metabolic pathways

11 of 3788

0.5

0.43

0.00022

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-446210

Synthesis of UDP-N-acetyl-glucosamine

5 of 7

2.9

5.26

1.58e-10

MAP-446219

Synthesis of substrates in N-glycan biosythesis

5 of 22

2.4

4.09

7.99e-09

MAP-446193

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

5 of 38

2.16

3.46

6.31e-08

MAP-446203

Asparagine N-linked glycosylation

5 of 161

1.53

1.71

4.62e-05

MAP-351202

Metabolism of polyamines

2 of 14

2.2

0.96

0.0168

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003764

N-acetylglucosamine-6-phosphate deacetylase

2 of 2

3.04

1.04

0.0136

IPR017932

Glutamine amidotransferase type 2 domain

2 of 6

2.56

0.83

0.0316

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