XA68_12430 protein (Ophiocordyceps unilateralis)

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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XA68_12430

Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (162 aa)

Predicted Functional Partners:

XA68_18541

0.998

XA68_13722

0.998

XA68_15419

0.995

XA68_18092

0.991

XA68_11517

0.990

XA68_12305

0.989

XA68_14600

0.988

XA68_12155

0.985

XA68_16712

0.984

XA68_10379

0.984

Your Current Organism:

Ophiocordyceps unilateralis

NCBI taxonomy Id: 268505
Other names: Cordyceps unilateralis, O. unilateralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
XA68_10379	XA68_12305	A0A2A9PGZ7	A0A2A9PEY8	Uncharacterized protein.	MI domain-containing protein.	0.981
XA68_10379	XA68_12430	A0A2A9PGZ7	A0A2A9PET4	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.984
XA68_10379	XA68_14600	A0A2A9PGZ7	A0A2A9PA04	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.984
XA68_10379	XA68_15419	A0A2A9PGZ7	A0A2A9P6U5	Uncharacterized protein.	SKIP_SNW domain-containing protein.	0.403
XA68_10379	XA68_16712	A0A2A9PGZ7	A0A2A9P645	Uncharacterized protein.	Uncharacterized protein.	0.984
XA68_10379	XA68_18092	A0A2A9PGZ7	A0A2A9PJQ9	Uncharacterized protein.	Uncharacterized protein.	0.905
XA68_10379	XA68_18541	A0A2A9PGZ7	A0A2A9P2Y1	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.982
XA68_11517	XA68_12155	A0A2A9PFG0	A0A2A9PPB9	PWI domain-containing protein.	Uncharacterized protein.	0.981
XA68_11517	XA68_12305	A0A2A9PFG0	A0A2A9PEY8	PWI domain-containing protein.	MI domain-containing protein.	0.989
XA68_11517	XA68_12430	A0A2A9PFG0	A0A2A9PET4	PWI domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.990
XA68_11517	XA68_13722	A0A2A9PFG0	A0A2A9PA60	PWI domain-containing protein.	Uncharacterized protein.	0.977
XA68_11517	XA68_14600	A0A2A9PFG0	A0A2A9PA04	PWI domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.913
XA68_11517	XA68_15419	A0A2A9PFG0	A0A2A9P6U5	PWI domain-containing protein.	SKIP_SNW domain-containing protein.	0.658
XA68_11517	XA68_16712	A0A2A9PFG0	A0A2A9P645	PWI domain-containing protein.	Uncharacterized protein.	0.870
XA68_11517	XA68_18092	A0A2A9PFG0	A0A2A9PJQ9	PWI domain-containing protein.	Uncharacterized protein.	0.977
XA68_11517	XA68_18541	A0A2A9PFG0	A0A2A9P2Y1	PWI domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.990
XA68_12155	XA68_11517	A0A2A9PPB9	A0A2A9PFG0	Uncharacterized protein.	PWI domain-containing protein.	0.981
XA68_12155	XA68_12430	A0A2A9PPB9	A0A2A9PET4	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.985
XA68_12155	XA68_13722	A0A2A9PPB9	A0A2A9PA60	Uncharacterized protein.	Uncharacterized protein.	0.988
XA68_12155	XA68_14600	A0A2A9PPB9	A0A2A9PA04	Uncharacterized protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.987

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Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016570

Histone modification

6 of 89

1.91

3.1

6.62e-08

GO:0016573

Histone acetylation

4 of 33

2.16

2.75

2.85e-06

GO:0045893

Positive regulation of transcription, DNA-templated

7 of 165

1.71

2.74

6.62e-08

GO:0051123

RNA polymerase II preinitiation complex assembly

3 of 24

2.17

2.03

0.00011

GO:0016578

Histone deubiquitination

2 of 2

3.08

1.94

0.00031

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003713

Transcription coactivator activity

4 of 20

2.38

2.78

4.57e-06

GO:0003712

Transcription coregulator activity

5 of 81

1.87

2.41

4.57e-06

GO:0046982

Protein heterodimerization activity

3 of 34

2.02

1.41

0.0018

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000124

SAGA complex

10 of 19

2.8

11.63

4.29e-24

GO:0046695

SLIK (SAGA-like) complex

3 of 5

2.86

3.2

1.28e-06

GO:0005669

Transcription factor TFIID complex

3 of 17

2.32

2.41

2.30e-05

GO:0043231

Intracellular membrane-bounded organelle

11 of 4898

0.43

0.36

0.00073

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3955

SAGA complex

8 of 17

2.75

8.53

1.66e-17

CL:3960

SAGA complex

6 of 11

2.81

6.68

1.83e-13

CL:3963

SAGA complex

4 of 6

2.9

4.29

1.15e-08

CL:4304

Transcription factor TFIID complex

3 of 10

2.56

2.48

2.35e-05

CL:4305

Transcription factor TFIID complex

2 of 5

2.68

1.49

0.0019

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03022

Basal transcription factors

3 of 72

1.7

1.14

0.0043

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5689880

Ub-specific processing proteases

4 of 77

1.79

1.61

0.00040

MAP-5688426

Deubiquitination

4 of 114

1.62

1.37

0.00091

MAP-76042

RNA Polymerase II Transcription Initiation And Promoter Clearance

3 of 51

1.85

1.24

0.0033

MAP-75953

RNA Polymerase II Transcription Initiation

3 of 51

1.85

1.24

0.0033

MAP-73779

RNA Polymerase II Transcription Pre-Initiation And Promoter Opening

3 of 51

1.85

1.24

0.0033

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070461

SAGA-type complex

6 of 15

2.68

6.08

1.73e-12

GOCC:0000124

SAGA complex

5 of 13

2.66

5.04

2.28e-10

GOCC:0005654

Nucleoplasm

10 of 287

1.62

3.52

3.17e-13

GOCC:1990234

Transferase complex

8 of 397

1.38

2.14

1.04e-08

GOCC:0071819

DUBm complex

2 of 3

2.9

1.9

0.00035

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0396

Initiation factor

3 of 41

1.94

1.44

0.0014

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR009072

Histone-fold

3 of 29

2.09

1.16

0.0064

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