XA68_11519 protein (Ophiocordyceps unilateralis)

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Predicted Interactions

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XA68_11519

GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (258 aa)

Predicted Functional Partners:

XA68_13678

0.999

XA68_13046

0.996

XA68_13544

0.994

XA68_10089

0.993

XA68_13563

0.992

XA68_15973

0.978

XA68_15972

0.978

XA68_15679

0.970

XA68_13336

0.970

XA68_10838

0.968

Your Current Organism:

Ophiocordyceps unilateralis

NCBI taxonomy Id: 268505
Other names: Cordyceps unilateralis, O. unilateralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
XA68_10089	XA68_10838	A0A2A9PNV5	A0A2A9P2I2	Xpo1 domain-containing protein.	RanBD1 domain-containing protein.	0.632
XA68_10089	XA68_11519	A0A2A9PNV5	A0A2A9PGR7	Xpo1 domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.993
XA68_10089	XA68_13046	A0A2A9PNV5	A0A2A9PBX9	Xpo1 domain-containing protein.	Importin N-terminal domain-containing protein.	0.509
XA68_10089	XA68_13336	A0A2A9PNV5	A0A2A9PBB4	Xpo1 domain-containing protein.	Uncharacterized protein.	0.670
XA68_10089	XA68_13544	A0A2A9PNV5	A0A2A9PCD9	Xpo1 domain-containing protein.	Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.	0.634
XA68_10089	XA68_13563	A0A2A9PNV5	A0A2A9PCE1	Xpo1 domain-containing protein.	Importin N-terminal domain-containing protein.	0.479
XA68_10089	XA68_13678	A0A2A9PNV5	A0A2A9PC52	Xpo1 domain-containing protein.	Uncharacterized protein.	0.466
XA68_10089	XA68_15679	A0A2A9PNV5	A0A2A9P7Z1	Xpo1 domain-containing protein.	Uncharacterized protein.	0.670
XA68_10089	XA68_15972	A0A2A9PNV5	A0A2A9P636	Xpo1 domain-containing protein.	RanBD1 domain-containing protein.	0.646
XA68_10089	XA68_15973	A0A2A9PNV5	A0A2A9P5V0	Xpo1 domain-containing protein.	Uncharacterized protein.	0.646
XA68_10838	XA68_10089	A0A2A9P2I2	A0A2A9PNV5	RanBD1 domain-containing protein.	Xpo1 domain-containing protein.	0.632
XA68_10838	XA68_11519	A0A2A9P2I2	A0A2A9PGR7	RanBD1 domain-containing protein.	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.968
XA68_10838	XA68_13046	A0A2A9P2I2	A0A2A9PBX9	RanBD1 domain-containing protein.	Importin N-terminal domain-containing protein.	0.936
XA68_10838	XA68_13336	A0A2A9P2I2	A0A2A9PBB4	RanBD1 domain-containing protein.	Uncharacterized protein.	0.879
XA68_10838	XA68_13563	A0A2A9P2I2	A0A2A9PCE1	RanBD1 domain-containing protein.	Importin N-terminal domain-containing protein.	0.821
XA68_10838	XA68_13678	A0A2A9P2I2	A0A2A9PC52	RanBD1 domain-containing protein.	Uncharacterized protein.	0.446
XA68_10838	XA68_15679	A0A2A9P2I2	A0A2A9P7Z1	RanBD1 domain-containing protein.	Uncharacterized protein.	0.879
XA68_11519	XA68_10089	A0A2A9PGR7	A0A2A9PNV5	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Xpo1 domain-containing protein.	0.993
XA68_11519	XA68_10838	A0A2A9PGR7	A0A2A9P2I2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	RanBD1 domain-containing protein.	0.968
XA68_11519	XA68_13046	A0A2A9PGR7	A0A2A9PBX9	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	Importin N-terminal domain-containing protein.	0.996

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140647

P450-containing electron transport chain

2 of 2

2.93

0.87

0.0273

GO:0006631

Fatty acid metabolic process

4 of 135

1.4

0.72

0.0273

GO:0006633

Fatty acid biosynthetic process

3 of 55

1.66

0.69

0.0439

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

3 of 24

2.02

1.17

0.0056

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4546

Mixed, incl. Valine, leucine and isoleucine degradation, and Fatty acid metabolic process

6 of 118

1.63

2.14

3.72e-06

CL:4547

Mixed, incl. Valine, leucine and isoleucine degradation, and TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain

5 of 109

1.59

1.88

1.88e-05

CL:4738

Mixed, incl. Thioesterase domain, and Quinone oxidoreductase/zeta-crystallin, conserved site

2 of 5

2.53

1.3

0.0041

CL:12660

Protein import into peroxisome matrix, and acyl-CoA binding

2 of 6

2.45

1.25

0.0050

CL:4676

Mixed, incl. Biotin-binding site, and Fatty acid metabolism

2 of 8

2.32

1.15

0.0074

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00061

Fatty acid biosynthesis

4 of 33

2.01

2.39

1.08e-05

map00780

Biotin metabolism

3 of 18

2.15

1.99

0.00013

map01212

Fatty acid metabolism

4 of 127

1.42

1.29

0.00060

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-2395516

Electron transport from NADPH to Ferredoxin

2 of 3

2.75

1.06

0.0119

MAP-9033241

Peroxisomal protein import

4 of 188

1.25

0.69

0.0244

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