STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XA68_16940Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (529 aa)    
Predicted Functional Partners:
XA68_13742
Endo/exonuclease/phosphatase domain-containing protein.
    
 0.872
XA68_16941
ADF-H domain-containing protein.
 
      0.822
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
  
 
 0.698
XA68_11918
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.631
XA68_10322
SAE2 domain-containing protein.
 
      0.625
XA68_18212
Checkpoint protein; Belongs to the HUS1 family.
    
 
 0.619
XA68_10412
DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
    
 
 0.594
XA68_11044
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
  
 0.592
XA68_12541
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
    
 
 0.571
XA68_14938
DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.
    
 
 0.540
Your Current Organism:
Ophiocordyceps unilateralis
NCBI taxonomy Id: 268505
Other names: Cordyceps unilateralis, O. unilateralis
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