STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ddhD-2-hydroxyacid dehydrogenase (NADP); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (307 aa)    
Predicted Functional Partners:
apt1
HGPRTase-like protein; May catalyze a purine salvage reaction, the substrate is unknown.
       0.576
thrC1
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 0.496
thrC3
Threonine synthase.
  
  
 0.496
hda1
HdaI-type histone deacetylase.
   
 0.464
hom
Homoserine dehydrogenase.
  
 
 0.449
Nmlp_2104
Uncharacterized protein.
       0.441
leuB
3-isopropylmalate dehydrogenase.
  
  
 0.438
purNH
Phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase.
  
 
 0.417
Nmlp_1087
Pyridoxal phosphate-dependent aminotransferase.
 
  
 0.405
rpl6
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.400
Your Current Organism:
Natronomonas moolapensis
NCBI taxonomy Id: 268739
Other names: N. moolapensis 8.8.11, Natronomonas moolapensis 8.8.11, Natronomonas moolapensis DSM 18674, Natronomonas moolapensis JCM 14361, Natronomonas moolapensis str. 8.8.11, Natronomonas moolapensis strain 8.8.11, haloarchaeon CSW8.8.11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.