node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nmlp_3169 | ilvB | Nmlp_3169 | Nmlp_3166 | Uncharacterized protein. | Acetolactate synthase large subunit. | 0.856 |
Nmlp_3169 | ilvC | Nmlp_3169 | Nmlp_3168 | Uncharacterized protein. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.857 |
Nmlp_3169 | ilvN | Nmlp_3169 | Nmlp_3167 | Uncharacterized protein. | Acetolactate synthase small subunit. | 0.857 |
Nmlp_3169 | leuB | Nmlp_3169 | Nmlp_3172 | Uncharacterized protein. | 3-isopropylmalate dehydrogenase. | 0.619 |
Nmlp_3169 | leuC | Nmlp_3169 | Nmlp_3170 | Uncharacterized protein. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.857 |
Nmlp_3169 | leuD | Nmlp_3169 | Nmlp_3171 | Uncharacterized protein. | 3-isopropylmalate dehydratase small subunit. | 0.723 |
ilvB | Nmlp_3169 | Nmlp_3166 | Nmlp_3169 | Acetolactate synthase large subunit. | Uncharacterized protein. | 0.856 |
ilvB | ilvC | Nmlp_3166 | Nmlp_3168 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
ilvB | ilvD | Nmlp_3166 | Nmlp_1521 | Acetolactate synthase large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.992 |
ilvB | ilvN | Nmlp_3166 | Nmlp_3167 | Acetolactate synthase large subunit. | Acetolactate synthase small subunit. | 0.999 |
ilvB | korB2 | Nmlp_3166 | Nmlp_3098 | Acetolactate synthase large subunit. | Oxoglutarate--ferredoxin oxidoreductase beta subunit. | 0.914 |
ilvB | leuA2 | Nmlp_3166 | Nmlp_1234 | Acetolactate synthase large subunit. | 2-isopropylmalate synthase / (R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.989 |
ilvB | leuB | Nmlp_3166 | Nmlp_3172 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydrogenase. | 0.989 |
ilvB | leuC | Nmlp_3166 | Nmlp_3170 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.961 |
ilvB | leuD | Nmlp_3166 | Nmlp_3171 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase small subunit. | 0.943 |
ilvB | porB | Nmlp_3166 | Nmlp_3264 | Acetolactate synthase large subunit. | Pyruvate--ferredoxin oxidoreductase beta subunit. | 0.914 |
ilvC | Nmlp_3169 | Nmlp_3168 | Nmlp_3169 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Uncharacterized protein. | 0.857 |
ilvC | ilvB | Nmlp_3168 | Nmlp_3166 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase large subunit. | 0.999 |
ilvC | ilvD | Nmlp_3168 | Nmlp_1521 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.996 |
ilvC | ilvN | Nmlp_3168 | Nmlp_3167 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Acetolactate synthase small subunit. | 0.999 |