STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthase; Belongs to the prokaryotic GSH synthase family. (313 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.942
Ecaj_0076
Glutamate-cysteine ligase-related protein.
 
  
 0.932
Ecaj_0241
Glutathione S- transferase, N-terminal.
 
  
 0.930
Ecaj_0095
Kef-type potassium/proton antiporter, CPA2 family; TC 2.A.37.1; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.597
Ecaj_0671
Transport-associated domain.
       0.537
Ecaj_0411
Transcriptional regulator, BadM/Rrf2 family.
     
 0.507
Ecaj_0319
Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal.
      
 0.467
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.455
Ecaj_0385
RNA polymerase, sigma 32 subunit, RpoH; Belongs to the sigma-70 factor family.
 
  
 0.427
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.405
Your Current Organism:
Ehrlichia canis
NCBI taxonomy Id: 269484
Other names: E. canis str. Jake, Ehrlichia canis Jake, Ehrlichia canis str. Jake, Ehrlichia canis strain Jake
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.