node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KPM51375.1 | KPM53044.1 | ACG83_35190 | ACG83_26975 | Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.673 |
KPM51375.1 | egtB | ACG83_35190 | ACG83_25730 | Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.655 |
KPM51590.1 | egtB | ACG83_32500 | ACG83_25730 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.717 |
KPM51590.1 | egtC | ACG83_32500 | ACG83_25735 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.777 |
KPM51590.1 | egtD | ACG83_32500 | ACG83_25740 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.769 |
KPM52249.1 | egtB | ACG83_27920 | ACG83_25730 | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.570 |
KPM53029.1 | egtB | ACG83_26865 | ACG83_25730 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.777 |
KPM53029.1 | egtC | ACG83_26865 | ACG83_25735 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.782 |
KPM53029.1 | egtD | ACG83_26865 | ACG83_25740 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.759 |
KPM53044.1 | KPM51375.1 | ACG83_26975 | ACG83_35190 | Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology. | Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.673 |
KPM53044.1 | egtB | ACG83_26975 | ACG83_25730 | Peptidase C69; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.637 |
KPM53572.1 | egtB | ACG83_23290 | ACG83_25730 | Arylsulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.577 |
KPM56596.1 | egtB | ACG83_01390 | ACG83_25730 | Arylsulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.575 |
egtA | egtB | ACG83_25725 | ACG83_25730 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.990 |
egtA | egtC | ACG83_25725 | ACG83_25735 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.960 |
egtA | egtD | ACG83_25725 | ACG83_25740 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.964 |
egtB | KPM51375.1 | ACG83_25730 | ACG83_35190 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Flavoprotein disulfide reductase; Catalyzes the reduction of nonspecific electron acceptors such as 2,6-dimethyl-1,4-benzoquinone and 5-hydroxy-1,4-naphthaquinone; does not have lipoamide dehydrogenase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.655 |
egtB | KPM51590.1 | ACG83_25730 | ACG83_32500 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.717 |
egtB | KPM52249.1 | ACG83_25730 | ACG83_27920 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.570 |
egtB | KPM53029.1 | ACG83_25730 | ACG83_26865 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.777 |