STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BQ2448_1239BQ2448_1239 protein. (530 aa)    
Predicted Functional Partners:
BQ2448_5366
BQ2448_5366 protein.
  
 
 0.801
BQ2448_2477
BQ2448_2477 protein.
    
 0.795
BQ2448_1816
BQ2448_1816 protein.
    
 0.718
BQ2448_5370
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.683
BQ2448_3153
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
    
 0.659
BQ2448_3961
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.632
BQ2448_1620
BQ2448_1620 protein.
  
 
 0.563
BQ2448_5311
BQ2448_5311 protein.
    
 0.558
BQ2448_498
BQ2448_498 protein.
    
 0.558
BQ2448_485
BQ2448_485 protein.
    
 0.558
Your Current Organism:
Microbotryum intermedium
NCBI taxonomy Id: 269621
Other names: HUV 3895, M. intermedium, Ustilago intermedia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.