BQ2448_865 protein (Microbotryum intermedium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

BQ2448_865

BQ2448_865 protein. (645 aa)

Predicted Functional Partners:

BQ2448_7614

0.666

BQ2448_6940

0.659

BQ2448_1160

0.652

BQ2448_2078

0.629

BQ2448_6188

0.618

BQ2448_6249

0.615

BQ2448_5653

0.614

BQ2448_1273

0.612

BQ2448_3319

0.610

BQ2448_8003

0.607

Your Current Organism:

Microbotryum intermedium

NCBI taxonomy Id: 269621
Other names: HUV 3895, M. intermedium, Ustilago intermedia

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BQ2448_1160	BQ2448_1273	A0A238FFA2	A0A238FAS4	BQ2448_1160 protein.	BQ2448_1273 protein.	0.994
BQ2448_1160	BQ2448_2078	A0A238FFA2	A0A238FD38	BQ2448_1160 protein.	BQ2448_2078 protein.	0.998
BQ2448_1160	BQ2448_3319	A0A238FFA2	A0A238FBM3	BQ2448_1160 protein.	BQ2448_3319 protein.	0.998
BQ2448_1160	BQ2448_5653	A0A238FFA2	A0A238F1T8	BQ2448_1160 protein.	BQ2448_5653 protein.	0.995
BQ2448_1160	BQ2448_6188	A0A238FFA2	A0A238FRB7	BQ2448_1160 protein.	BQ2448_6188 protein.	0.999
BQ2448_1160	BQ2448_6249	A0A238FFA2	A0A238FM12	BQ2448_1160 protein.	BQ2448_6249 protein; Belongs to the PI3/PI4-kinase family.	0.996
BQ2448_1160	BQ2448_8003	A0A238FFA2	A0A238FSZ1	BQ2448_1160 protein.	BQ2448_8003 protein.	0.998
BQ2448_1160	BQ2448_865	A0A238FFA2	A0A238FA43	BQ2448_1160 protein.	BQ2448_865 protein.	0.652
BQ2448_1273	BQ2448_1160	A0A238FAS4	A0A238FFA2	BQ2448_1273 protein.	BQ2448_1160 protein.	0.994
BQ2448_1273	BQ2448_2078	A0A238FAS4	A0A238FD38	BQ2448_1273 protein.	BQ2448_2078 protein.	0.997
BQ2448_1273	BQ2448_3319	A0A238FAS4	A0A238FBM3	BQ2448_1273 protein.	BQ2448_3319 protein.	0.996
BQ2448_1273	BQ2448_5653	A0A238FAS4	A0A238F1T8	BQ2448_1273 protein.	BQ2448_5653 protein.	0.992
BQ2448_1273	BQ2448_6188	A0A238FAS4	A0A238FRB7	BQ2448_1273 protein.	BQ2448_6188 protein.	0.997
BQ2448_1273	BQ2448_6249	A0A238FAS4	A0A238FM12	BQ2448_1273 protein.	BQ2448_6249 protein; Belongs to the PI3/PI4-kinase family.	0.996
BQ2448_1273	BQ2448_6940	A0A238FAS4	A0A238FIM8	BQ2448_1273 protein.	BQ2448_6940 protein.	0.597
BQ2448_1273	BQ2448_8003	A0A238FAS4	A0A238FSZ1	BQ2448_1273 protein.	BQ2448_8003 protein.	0.996
BQ2448_1273	BQ2448_865	A0A238FAS4	A0A238FA43	BQ2448_1273 protein.	BQ2448_865 protein.	0.612
BQ2448_2078	BQ2448_1160	A0A238FD38	A0A238FFA2	BQ2448_2078 protein.	BQ2448_1160 protein.	0.998
BQ2448_2078	BQ2448_1273	A0A238FD38	A0A238FAS4	BQ2448_2078 protein.	BQ2448_1273 protein.	0.997
BQ2448_2078	BQ2448_3319	A0A238FD38	A0A238FBM3	BQ2448_2078 protein.	BQ2448_3319 protein.	0.998

page 1 of 5

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000724

Double-strand break repair via homologous recombination

3 of 4

2.43

1.93

0.00054

GO:0006281

DNA repair

4 of 50

1.46

1.23

0.0020

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003690

Double-stranded DNA binding

3 of 14

1.89

1.25

0.0057

GO:0003678

DNA helicase activity

3 of 14

1.89

1.25

0.0057

GO:0004527

Exonuclease activity

3 of 20

1.73

1.2

0.0057

GO:0016887

ATP hydrolysis activity

3 of 41

1.42

0.86

0.0179

GO:0008408

3-5 exonuclease activity

2 of 9

1.9

0.86

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033202

DNA helicase complex

3 of 8

2.13

2.0

0.00027

GO:1902494

Catalytic complex

4 of 68

1.33

1.21

0.00092

GO:0032991

Protein-containing complex

5 of 170

1.03

0.88

0.0011

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1230

PD-(D/E)XK nuclease superfamily, and CBS domain

4 of 6

2.38

3.11

3.40e-06

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0033202

DNA helicase complex

3 of 13

1.92

1.48

0.0020

GOCC:0044815

DNA packaging complex

3 of 15

1.86

1.46

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0269

Exonuclease

3 of 11

1.99

1.9

0.00033

KW-0234

DNA repair

4 of 31

1.67

1.72

0.00024

KW-0227

DNA damage

4 of 31

1.67

1.72

0.00024

KW-0347

Helicase

3 of 20

1.73

1.5

0.0012

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13361

UvrD-like helicase C-terminal domain

3 of 3

2.56

2.31

0.00013

PF12705

PD-(D/E)XK nuclease superfamily

3 of 4

2.43

2.28

0.00013

PF13245

AAA domain

2 of 5

2.16

0.99

0.0212

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038726

PD-(D/E)XK endonuclease-like domain, AddAB-type

3 of 4

2.43

1.92

0.00058

IPR011604

PD-(D/E)XK endonuclease-like domain superfamily

3 of 4

2.43

1.92

0.00058

IPR011335

Restriction endonuclease type II-like

3 of 7

2.19

1.82

0.00067

IPR014016

UvrD-like helicase, ATP-binding domain

3 of 8

2.13

1.8

0.00068

IPR000212

DNA helicase, UvrD/REP type

3 of 8

2.13

1.8

0.00068

(more ...)

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