STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BQ2448_1852BQ2448_1852 protein; Belongs to the ubiquitin-conjugating enzyme family. (95 aa)    
Predicted Functional Partners:
BQ2448_4635
BQ2448_4635 protein.
    
 
 0.925
BQ2448_2234
BQ2448_2234 protein.
    
 0.907
BQ2448_768
BQ2448_768 protein.
    
 0.901
BQ2448_461
ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.
    
 
 0.893
BQ2448_7307
BQ2448_7307 protein.
    
   0.888
BQ2448_3252
BQ2448_3252 protein; Belongs to the ubiquitin-conjugating enzyme family.
    
0.818
BQ2448_3592
BQ2448_3592 protein.
    
 0.817
BQ2448_3675
BQ2448_3675 protein.
    
 0.817
BQ2448_3339
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.772
BQ2448_2824
BQ2448_2824 protein.
    
 0.772
Your Current Organism:
Microbotryum intermedium
NCBI taxonomy Id: 269621
Other names: HUV 3895, M. intermedium, Ustilago intermedia
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.