STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BQ2448_7571Elongation of fatty acids protein. (356 aa)    
Predicted Functional Partners:
BQ2448_5515
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
 
 
 0.915
BQ2448_6202
BQ2448_6202 protein.
 
  
 0.914
BQ2448_1708
BQ2448_1708 protein.
    
 0.776
BQ2448_782
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
    
 0.735
BQ2448_2384
BQ2448_2384 protein.
     
 0.725
BQ2448_978
BQ2448_978 protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.595
BQ2448_7616
BQ2448_7616 protein.
     
 0.595
BQ2448_2607
Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily.
   
 0.586
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
  0.569
BQ2448_1468
BQ2448_1468 protein.
    
 0.561
Your Current Organism:
Microbotryum intermedium
NCBI taxonomy Id: 269621
Other names: HUV 3895, M. intermedium, Ustilago intermedia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.