node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFI28551.1 | SFI30012.1 | SAMN02799642_01384 | SAMN02799642_01443 | Glutamate synthase (NADPH/NADH) large chain. | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.872 |
SFI28551.1 | argD | SAMN02799642_01384 | SAMN02799642_03656 | Glutamate synthase (NADPH/NADH) large chain. | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.565 |
SFI28551.1 | proA | SAMN02799642_01384 | SAMN02799642_01305 | Glutamate synthase (NADPH/NADH) large chain. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.855 |
SFI28551.1 | proB | SAMN02799642_01384 | SAMN02799642_01304 | Glutamate synthase (NADPH/NADH) large chain. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.877 |
SFI28551.1 | proC | SAMN02799642_01384 | SAMN02799642_05319 | Glutamate synthase (NADPH/NADH) large chain. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.525 |
SFI28551.1 | purQ | SAMN02799642_01384 | SAMN02799642_03505 | Glutamate synthase (NADPH/NADH) large chain. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.744 |
SFI30012.1 | SFI28551.1 | SAMN02799642_01443 | SAMN02799642_01384 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate synthase (NADPH/NADH) large chain. | 0.872 |
SFI30012.1 | argD | SAMN02799642_01443 | SAMN02799642_03656 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.859 |
SFI30012.1 | proA | SAMN02799642_01443 | SAMN02799642_01305 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.847 |
SFI30012.1 | proB | SAMN02799642_01443 | SAMN02799642_01304 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.851 |
SFI30012.1 | proC | SAMN02799642_01443 | SAMN02799642_05319 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.885 |
SFI30012.1 | purQ | SAMN02799642_01443 | SAMN02799642_03505 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.753 |
SFI32200.1 | proA | SAMN02799642_01530 | SAMN02799642_01305 | Serine/threonine protein kinase. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.776 |
argD | SFI28551.1 | SAMN02799642_03656 | SAMN02799642_01384 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate synthase (NADPH/NADH) large chain. | 0.565 |
argD | SFI30012.1 | SAMN02799642_03656 | SAMN02799642_01443 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.859 |
argD | proA | SAMN02799642_03656 | SAMN02799642_01305 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.871 |
argD | proB | SAMN02799642_03656 | SAMN02799642_01304 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.830 |
argD | proC | SAMN02799642_03656 | SAMN02799642_05319 | acetylornithine/N-succinyldiaminopimelate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.593 |
atpA | nadD | SAMN02799642_02388 | SAMN02799642_01306 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.479 |
atpA | proA | SAMN02799642_02388 | SAMN02799642_01305 | ATP synthase F1 subcomplex alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.862 |