STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABStage II sporulation protein AB (anti-sigma F factor); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (146 aa)    
Predicted Functional Partners:
SFF94677.1
Anti-anti-sigma regulatory factor, SpoIIAA; Belongs to the anti-sigma-factor antagonist family.
 
 0.999
SFF94703.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.988
SFG97794.1
Anti-sigma B factor antagonist; Belongs to the anti-sigma-factor antagonist family.
  
 0.977
SFG97776.1
sigma-B regulation protein RsbU (phosphoserine phosphatase).
  
 0.902
SFG97836.1
RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family.
 
 
 0.890
SFF94734.1
Stage V sporulation protein AC.
 
   
 0.879
SFF94746.1
Stage V sporulation protein AD.
 
   
 0.871
SFF94761.1
Stage V sporulation protein AE.
 
     0.869
SFG39644.1
RNA polymerase sporulation-specific sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.844
SFF94771.1
Stage V sporulation protein AF.
 
   
 0.838
Your Current Organism:
Sporolactobacillus nakayamae
NCBI taxonomy Id: 269670
Other names: ATCC 700379, CCUG 41660, CIP 105319, DSM 11696, JCM 3514, LMG 18787, LMG:18787, NBRC 101526, S. nakayamae, strain M-114
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