STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pylSPyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (419 aa)    
Predicted Functional Partners:
pylB
Biotin synthase; Catalyzes the isomerization of L-lysine to (2R,3R)-3- methylornithine via a radical-based mechanism, a step in the biosynthesis pathway of pyrrolysine.
 
   
 0.970
ABF82161.3
Monomethylamine methyltransferase.
 
   
 0.922
mtmB1
Monomethylamine:corrinoid methyltransferase; Catalyzes the transfer of the methyl group from monomethylamine to the corrinoid cofactor of MtmC.
 
   
 0.901
AAZ69812.1
Conserved hypothetical protein.
 
   
 0.875
AAZ69813.1
Conserved hypothetical protein.
 
   
 0.874
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
      
 0.841
AAZ70458.1
Trimethylamine permease.
  
   
 0.711
serS2
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
  
   
 0.698
AAZ69651.1
Conserved hypothetical protein.
 
   
 0.695
cysS
cysteinyl-tRNA synthetase.
  
   
 0.695
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.