STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfnAPyridoxal-dependent decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily. (395 aa)    
Predicted Functional Partners:
AAZ71307.1
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.945
AAZ72309.1
Conserved hypothetical protein.
 
  
 0.932
AAZ72135.1
Pantothenate synthetase.
 
  
 0.931
AAZ71647.1
Glutamate decarboxylase.
  
  
 
0.922
AAZ71014.1
Aminotransferase.
  
 
 0.919
AAZ72019.1
Aminotransferase.
  
 
 0.919
hisC
Histidinol phosphate aminotransferase apoenzyme.
    
 0.909
AAZ71182.1
Asparagine synthetase (glutamine-hydrolyzing).
 
  
 0.870
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
    
 0.828
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.819
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.