STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AAZ71936.1NAD-dependent malic enzyme. (427 aa)    
Predicted Functional Partners:
AAZ71337.1
Fumarase beta subunit.
 
 0.983
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.948
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.948
AAZ69160.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.944
AAZ71338.1
Fumarase alpha subunit.
 
 
 0.943
AAZ70534.1
Pyruvate carboxylase subunit A.
  
 0.931
AAZ71140.1
2-oxoacid ferredoxin oxidoreductase, subunit alpha.
  
 
 0.919
porA
Pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.916
AAZ70533.1
Pyruvate carboxylase subunit B.
    
 0.916
AAZ71141.1
2-oxoacid ferredoxin oxidoreductase, subunit beta.
    
 0.916
Your Current Organism:
Methanosarcina barkeri Fusaro
NCBI taxonomy Id: 269797
Other names: M. barkeri str. Fusaro, Methanosarcina barkeri DSM 804, Methanosarcina barkeri str. Fusaro, Methanosarcina barkeri strain Fusaro
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