STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHU_2948Conserved hypothetical protein. (861 aa)    
Predicted Functional Partners:
yegD
Probable heat shock protein.
   
 0.985
dnaK
Chaperone protein (heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.985
CHU_1120
Membrane protein.
    
 0.972
groEL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.860
ppiC
Peptidylprolyl isomerase A (peptidyl-prolyl cis-trans isomerase); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.834
ppiA
Peptidyl-prolyl cis-trans isomerase, cyclophilin-binding protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.834
CHU_0323
Deacetylase.
    
 0.815
dnaJ-2
DNAJ-like chaperone; heat shock protein.
  
 0.807
dnaJ-3
DNAJ class chaperone; heat shock protein.
  
 0.807
dnaJ
Molecular chaperone, heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]
  
 0.798
Your Current Organism:
Cytophaga hutchinsonii
NCBI taxonomy Id: 269798
Other names: C. hutchinsonii ATCC 33406, Cytophaga hutchinsonii ATCC 33406, Cytophaga hutchinsonii str. ATCC 33406, Cytophaga hutchinsonii strain ATCC 33406
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