STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoD-2RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (201 aa)    
Predicted Functional Partners:
CHU_3696
Hypothetical protein.
       0.796
nth
DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.793
rpoE-2
RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.765
rpoE-6
RNA polymerase, sigma-E factor; heat shock and oxidative stress; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.759
rpoE-8
RNA polymerase sigma-70 factor, ECF subfamily.
  
     0.742
rpoE
RNA polymerase, sigma-E factor; heat shock and oxidative stress; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.553
CHU_3097
Possible ECF-family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.503
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.431
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.413
Your Current Organism:
Cytophaga hutchinsonii
NCBI taxonomy Id: 269798
Other names: C. hutchinsonii ATCC 33406, Cytophaga hutchinsonii ATCC 33406, Cytophaga hutchinsonii str. ATCC 33406, Cytophaga hutchinsonii strain ATCC 33406
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.