node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gmet_3149 | gcvH | Gmet_3149 | Gmet_3154 | Protein of unknown function DUF107. | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.621 |
Gmet_3149 | gcvP1 | Gmet_3149 | Gmet_3153 | Protein of unknown function DUF107. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.608 |
Gmet_3149 | gcvP2 | Gmet_3149 | Gmet_3152 | Protein of unknown function DUF107. | Glycine cleavage system P protein, subunit 2. | 0.607 |
Gmet_3149 | gcvT | Gmet_3149 | Gmet_3155 | Protein of unknown function DUF107. | Glycine cleavage system T protein. | 0.541 |
Gmet_3149 | lipA | Gmet_3149 | Gmet_3150 | Protein of unknown function DUF107. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.594 |
Gmet_3149 | lplA | Gmet_3149 | Gmet_3151 | Protein of unknown function DUF107. | Lipoate--protein ligase A. | 0.594 |
aceF | gcvH | Gmet_2752 | Gmet_3154 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.673 |
aceF | gcvT | Gmet_2752 | Gmet_3155 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Glycine cleavage system T protein. | 0.698 |
aceF | larG | Gmet_2752 | Gmet_0985 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Lipoyl carrier protein LarG; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.673 |
aceF | lipA | Gmet_2752 | Gmet_3150 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.565 |
aceF | lipB | Gmet_2752 | Gmet_2747 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Octanoyl-(acyl carrier protein)--protein octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.845 |
aceF | lplA | Gmet_2752 | Gmet_3151 | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | Lipoate--protein ligase A. | 0.774 |
gcvH | Gmet_3149 | Gmet_3154 | Gmet_3149 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Protein of unknown function DUF107. | 0.621 |
gcvH | aceF | Gmet_3154 | Gmet_2752 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase. | 0.673 |
gcvH | gcvP1 | Gmet_3154 | Gmet_3153 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
gcvH | gcvP2 | Gmet_3154 | Gmet_3152 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P protein, subunit 2. | 0.999 |
gcvH | gcvT | Gmet_3154 | Gmet_3155 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein. | 0.999 |
gcvH | larG | Gmet_3154 | Gmet_0985 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoyl carrier protein LarG; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.907 |
gcvH | lipA | Gmet_3154 | Gmet_3150 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.940 |
gcvH | lipB | Gmet_3154 | Gmet_2747 | Glycine cleavage system lipoyl carrier protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Octanoyl-(acyl carrier protein)--protein octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.698 |