STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (287 aa)    
Predicted Functional Partners:
ispE
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
  
 0.990
Tfu_0398
TatD-related deoxyribonuclease.
  
 0.880
ychF
Conserved hypothetical protein 92; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
 
  
 0.807
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.758
rpsD
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.756
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.749
rpsE
SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
 
 
 0.743
rsmG
Glucose inhibited division protein; Specifically methylates the N7 position of guanine in position 518 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
     
 0.739
rpsI
SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family.
 
 
 
 0.733
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.725
Your Current Organism:
Thermobifida fusca
NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX
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