STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tfu_0587ABC transporter, permease protein. (200 aa)    
Predicted Functional Partners:
Tfu_0589
ABC-type cobalt transport system.
 
  
 0.974
Tfu_0588
ATPase.
 
  
 0.966
Tfu_2953
Putative transcriptional regulator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
  
 0.535
Tfu_2887
Similar to membrane protein.
  
     0.491
Tfu_2312
Putative cobalt transport system permease protein.
  
  
 0.448
Tfu_1924
Conserved hypothetical protein.
 
     0.438
Tfu_3047
Phosphoesterase, PA-phosphatase related.
  
     0.431
thiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.425
Tfu_0590
Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.418
Tfu_0591
Conserved hypothetical protein.
       0.418
Your Current Organism:
Thermobifida fusca
NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX
Server load: low (22%) [HD]