STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tfu_18433-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (234 aa)    
Predicted Functional Partners:
Tfu_1973
(Acyl-carrier protein) S-malonyltransferase.
 0.980
Tfu_1976
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 0.976
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.968
Tfu_1231
Modular polyketide synthase.
 
 0.960
Tfu_1841
Putative 3-ketoacyl-CoA reductase.
 
  
 
0.959
Tfu_1229
Putative 3-oxoacyl-ACP synthase III.
  
 
 0.918
Tfu_2308
Putative 3-oxoacyl-ACP reductase.
  
  
 
0.911
Tfu_1842
Enoyl-[acyl-carrier-protein] reductase (NADH).
 
  
0.755
Tfu_1218
Actinorhodin polyketide beta-ketoacyl synthase alpha subunit / 3-oxoacyl-ACP synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.722
Tfu_1219
Actinorhodin polyketide beta-ketoacyl synthase beta subunit / 3-oxoacyl-ACP synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.678
Your Current Organism:
Thermobifida fusca
NCBI taxonomy Id: 269800
Other names: T. fusca YX, Thermobifida fusca YX, Thermobifida fusca str. YX, Thermobifida fusca strain YX
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