STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltPSodium:dicarboxylate symporter; 237c0010; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (448 aa)    
Predicted Functional Partners:
gltP-2
C4-dicarboxylate transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
  
 
0.903
nagC
Transcriptional regulator; 237c0009; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.812
sdhD
Succinate dehydrogenase; 155c0005; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.684
lrp-6
AsnC family transcriptional regulator; 237c0008; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.615
putP
Sodium:solute symporter; 16d0001; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.563
sfcA
Malic enzyme; 150d0021; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.535
gltA
257d0002; type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase [...]
  
  
 0.473
potE-2
Amino acid transporter; 167d0024; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.472
putA-10
Integrase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
  
 0.440
ptsA
PTS fructose transporter subunit IIA; 98c0009; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.428
Your Current Organism:
Methylobacterium aquaticum
NCBI taxonomy Id: 270351
Other names: CCM 7218, CECT 5998, CIP 108333, DSM 16371, M. aquaticum, Methylobacterium aquaticum Gallego et al. 2005, strain GR16
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