STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amtBAmmonia channel protein; 392c0002; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)    
Predicted Functional Partners:
glnK
Nitrogen regulatory protein P-II 1; 1d0009; indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
glnK-2
Nitrogen regulatory protein P-II 1; 392c0003; indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
ntrB
ATPase; 198d0002; Derived by automated computational analysis using gene prediction method: Protein Homology. Start codon location was manually corrected by using GenomeMatcher.
  
 
 0.804
gltB-4
Glutamate synthase; 174d0002; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.796
nifH
Protochlorophyllide oxidoreductase; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
  
  
 0.720
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.675
nifD-2
Light-independent protochlorophyllide reductasesubunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
   
  
 0.610
ureA
Urease, gamma subunit; 150d0012; CDS was addded manually by using GenomeMatcher; Belongs to the urease beta subunit family.
  
  
 0.577
amiR
Chemotaxis protein CheY; 86d0009; Derived by automated computational analysis using gene prediction method: Protein Homology. Start codon location was manually corrected by using GenomeMatcher.
  
  
 0.572
gltB-2
Protein glxC; 347d0025; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.553
Your Current Organism:
Methylobacterium aquaticum
NCBI taxonomy Id: 270351
Other names: CCM 7218, CECT 5998, CIP 108333, DSM 16371, M. aquaticum, Methylobacterium aquaticum Gallego et al. 2005, strain GR16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.