node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAQ48365.1 | folE | Maq22A_c27700 | Maq22A_c15540 | 6-carboxy-5,6,7,8-tetrahydropterin synthase; 68c0003; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.967 |
folB | folE | Maq22A_c05245 | Maq22A_c15540 | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.979 |
folB | folK | Maq22A_c05245 | Maq22A_c05240 | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
folB | folP | Maq22A_c05245 | Maq22A_c05250 | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folB | folP-2 | Maq22A_c05245 | Maq22A_c16375 | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; 434c0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.872 |
folB | ribB | Maq22A_c05245 | Maq22A_c15490 | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.582 |
folE | BAQ48365.1 | Maq22A_c15540 | Maq22A_c27700 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; 68c0003; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.967 |
folE | folB | Maq22A_c15540 | Maq22A_c05245 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.979 |
folE | folK | Maq22A_c15540 | Maq22A_c05240 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
folE | folP | Maq22A_c15540 | Maq22A_c05250 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.975 |
folE | folP-2 | Maq22A_c15540 | Maq22A_c16375 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; 434c0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.872 |
folE | hisI | Maq22A_c15540 | Maq22A_c15535 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.851 |
folE | moaA | Maq22A_c15540 | Maq22A_c12010 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.914 |
folE | ndk | Maq22A_c15540 | Maq22A_c19680 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.853 |
folE | ribA | Maq22A_c15540 | Maq22A_c00175 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.932 |
folE | ribB | Maq22A_c15540 | Maq22A_c15490 | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.951 |
folK | folB | Maq22A_c05240 | Maq22A_c05245 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
folK | folE | Maq22A_c05240 | Maq22A_c15540 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; 262d0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
folK | folP | Maq22A_c05240 | Maq22A_c05250 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folK | folP-2 | Maq22A_c05240 | Maq22A_c16375 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; 11c0056; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; 434c0004; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |