STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAQ46465.1Transketolase; 87c0005; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)    
Predicted Functional Partners:
BAQ46466.1
Transketolase; 87c0006; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
mipB
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
 
 
 0.976
rpe
Ribulose-phosphate 3-epimerase; 151c0004; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.944
fabG-32
Short-chain dehydrogenase; 87c0007; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.941
tktA
Transketolase; 86c0005; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family.
 
 
0.937
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.915
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.913
prsA
Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
  0.913
rbsK-3
Sugar kinases, ribokinase family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
  0.908
pfkA
Pyrophosphate--fructose-6-phosphate1- phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
  0.905
Your Current Organism:
Methylobacterium aquaticum
NCBI taxonomy Id: 270351
Other names: CCM 7218, CECT 5998, CIP 108333, DSM 16371, M. aquaticum, Methylobacterium aquaticum Gallego et al. 2005, strain GR16
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