STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrBATPase; 198d0002; Derived by automated computational analysis using gene prediction method: Protein Homology. Start codon location was manually corrected by using GenomeMatcher. (382 aa)    
Predicted Functional Partners:
atoC-3
Chemotaxis protein CheY; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.997
glnK
Nitrogen regulatory protein P-II 1; 1d0009; indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
baeS-46
Histidine kinase; 169c0016; Derived by automated computational analysis using gene prediction method: Protein Homology. Start codon location was manually corrected by using GenomeMatcher.
 
 
0.876
BAQ46618.1
Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.867
glnK-2
Nitrogen regulatory protein P-II 1; 392c0003; indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.812
amtB
Ammonia channel protein; 392c0002; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.804
baeS-35
Histidine kinase; 220c0054; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.785
cheY-17
MFS transporter; 273d0002; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.668
baeS-42
Histidine kinase; 17d0002; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.665
atoC-6
ATPase AAA; 182c0002; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.653
Your Current Organism:
Methylobacterium aquaticum
NCBI taxonomy Id: 270351
Other names: CCM 7218, CECT 5998, CIP 108333, DSM 16371, M. aquaticum, Methylobacterium aquaticum Gallego et al. 2005, strain GR16
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