node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHK_1744 | CHK_2323 | CHK_1744 | CHK_2323 | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.661 |
CHK_1744 | ffh | CHK_1744 | CHK_2880 | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.894 |
CHK_1744 | ftsY | CHK_1744 | CHK_2877 | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | Signal recognition particle receptor protein FtsY, alpha subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.911 |
CHK_1744 | secA | CHK_1744 | CHK_2215 | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | Protein export cytoplasm protein SecA ATPase RNA helicase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.906 |
CHK_1744 | secY | CHK_1744 | CHK_2947 | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.919 |
CHK_2321 | CHK_2323 | CHK_2321 | CHK_2323 | Putative histidinol phosphatase and related hydrolases of the PHP family. | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | 0.652 |
CHK_2321 | CHK_2325 | CHK_2321 | CHK_2325 | Putative histidinol phosphatase and related hydrolases of the PHP family. | Uracil-DNA glycosylase, family 4. | 0.522 |
CHK_2321 | CHK_2326 | CHK_2321 | CHK_2326 | Putative histidinol phosphatase and related hydrolases of the PHP family. | Uracil-DNA glycosylase family protein, clostridial type. | 0.522 |
CHK_2321 | dnaX | CHK_2321 | CHK_2322 | Putative histidinol phosphatase and related hydrolases of the PHP family. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.649 |
CHK_2321 | recR | CHK_2321 | CHK_2324 | Putative histidinol phosphatase and related hydrolases of the PHP family. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.577 |
CHK_2323 | CHK_1744 | CHK_2323 | CHK_1744 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Preprotein translocase subunit YajC; TCDB 3.A.5.1.1. | 0.661 |
CHK_2323 | CHK_2321 | CHK_2323 | CHK_2321 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Putative histidinol phosphatase and related hydrolases of the PHP family. | 0.652 |
CHK_2323 | CHK_2325 | CHK_2323 | CHK_2325 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Uracil-DNA glycosylase, family 4. | 0.726 |
CHK_2323 | CHK_2326 | CHK_2323 | CHK_2326 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Uracil-DNA glycosylase family protein, clostridial type. | 0.726 |
CHK_2323 | dnaX | CHK_2323 | CHK_2322 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.897 |
CHK_2323 | ffh | CHK_2323 | CHK_2880 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Signal recognition particle, subunit Ffh SRP54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.697 |
CHK_2323 | ftsY | CHK_2323 | CHK_2877 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Signal recognition particle receptor protein FtsY, alpha subunit; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.705 |
CHK_2323 | recR | CHK_2323 | CHK_2324 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.979 |
CHK_2323 | secA | CHK_2323 | CHK_2215 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Protein export cytoplasm protein SecA ATPase RNA helicase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.612 |
CHK_2323 | secY | CHK_2323 | CHK_2947 | Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.621 |