STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHK_2805Putative Na+/H+ antiporter. (410 aa)    
Predicted Functional Partners:
CHK_1316
Chloride channel protein.
     
 0.632
CHK_2273
Xylose isomerase.
   
 
  0.575
CHK_0399
Ammonium transporter; Belongs to the P(II) protein family.
   
 
 0.556
CHK_0895
Catabolite repression HPr-like protein Crh.
    
  0.484
CHK_1815
Catabolite repression HPr-like protein Crh.
    
  0.484
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.470
dinB-3
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
     
 0.458
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.442
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.442
CHK_1308
Pyruvate-flavodoxin oxidoreductase.
     
 0.437
Your Current Organism:
Catabacter hongkongensis
NCBI taxonomy Id: 270498
Other names: C. hongkongensis, CCUG 54229, Catabacter hongkongensis Lau et al. 2014, JCM 17853, strain HKU16
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