node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEI00611.1 | dnaE | SAMN05216535_3323 | SAMN05216535_1621 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit alpha. | 0.965 |
SEI00611.1 | dnaN | SAMN05216535_3323 | SAMN05216535_0350 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.962 |
SEI00611.1 | dnaQ | SAMN05216535_3323 | SAMN05216535_2198 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.808 |
SEI00611.1 | dnaX | SAMN05216535_3323 | SAMN05216535_2109 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.979 |
SEI00611.1 | holA | SAMN05216535_3323 | SAMN05216535_3899 | DNA polymerase III, chi subunit. | DNA polymerase III, delta subunit. | 0.983 |
SEI00611.1 | holB | SAMN05216535_3323 | SAMN05216535_1721 | DNA polymerase III, chi subunit. | DNA polymerase-3 subunit delta'. | 0.981 |
SEI00611.1 | rnt | SAMN05216535_3323 | SAMN05216535_1394 | DNA polymerase III, chi subunit. | RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.725 |
SEI00611.1 | ssb | SAMN05216535_3323 | SAMN05216535_0941 | DNA polymerase III, chi subunit. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.920 |
dnaE | SEI00611.1 | SAMN05216535_1621 | SAMN05216535_3323 | DNA polymerase-3 subunit alpha. | DNA polymerase III, chi subunit. | 0.965 |
dnaE | dnaN | SAMN05216535_1621 | SAMN05216535_0350 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.976 |
dnaE | dnaQ | SAMN05216535_1621 | SAMN05216535_2198 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.966 |
dnaE | dnaX | SAMN05216535_1621 | SAMN05216535_2109 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.977 |
dnaE | holA | SAMN05216535_1621 | SAMN05216535_3899 | DNA polymerase-3 subunit alpha. | DNA polymerase III, delta subunit. | 0.968 |
dnaE | holB | SAMN05216535_1621 | SAMN05216535_1721 | DNA polymerase-3 subunit alpha. | DNA polymerase-3 subunit delta'. | 0.971 |
dnaE | ligA | SAMN05216535_1621 | SAMN05216535_2147 | DNA polymerase-3 subunit alpha. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.776 |
dnaE | rnt | SAMN05216535_1621 | SAMN05216535_1394 | DNA polymerase-3 subunit alpha. | RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.886 |
dnaE | rpoC | SAMN05216535_1621 | SAMN05216535_0903 | DNA polymerase-3 subunit alpha. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.764 |
dnaE | ssb | SAMN05216535_1621 | SAMN05216535_0941 | DNA polymerase-3 subunit alpha. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.951 |
dnaN | SEI00611.1 | SAMN05216535_0350 | SAMN05216535_3323 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase III, chi subunit. | 0.962 |
dnaN | dnaE | SAMN05216535_0350 | SAMN05216535_1621 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase-3 subunit alpha. | 0.976 |