node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH93495.1 | adk | SAMN05216535_2786 | SAMN05216535_3214 | Glutaredoxin-like domain. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.553 |
SEH93495.1 | dut | SAMN05216535_2786 | SAMN05216535_0694 | Glutaredoxin-like domain. | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.546 |
SEH93495.1 | ndk | SAMN05216535_2786 | SAMN05216535_3299 | Glutaredoxin-like domain. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.533 |
SEH93495.1 | nrdA | SAMN05216535_2786 | SAMN05216535_3145 | Glutaredoxin-like domain. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.956 |
adk | SEH93495.1 | SAMN05216535_3214 | SAMN05216535_2786 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Glutaredoxin-like domain. | 0.553 |
adk | cmk | SAMN05216535_3214 | SAMN05216535_2084 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Cytidylate kinase. | 0.798 |
adk | dut | SAMN05216535_3214 | SAMN05216535_0694 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.768 |
adk | gmk | SAMN05216535_3214 | SAMN05216535_0685 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.966 |
adk | grxC | SAMN05216535_3214 | SAMN05216535_0129 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.612 |
adk | ndk | SAMN05216535_3214 | SAMN05216535_3299 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.811 |
adk | nrdA | SAMN05216535_3214 | SAMN05216535_3145 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.895 |
adk | nrdB | SAMN05216535_3214 | SAMN05216535_3146 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.863 |
cmk | adk | SAMN05216535_2084 | SAMN05216535_3214 | Cytidylate kinase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.798 |
cmk | dut | SAMN05216535_2084 | SAMN05216535_0694 | Cytidylate kinase. | dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.477 |
cmk | gmk | SAMN05216535_2084 | SAMN05216535_0685 | Cytidylate kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.658 |
cmk | grxC | SAMN05216535_2084 | SAMN05216535_0129 | Cytidylate kinase. | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. | 0.521 |
cmk | ndk | SAMN05216535_2084 | SAMN05216535_3299 | Cytidylate kinase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.880 |
cmk | nrdA | SAMN05216535_2084 | SAMN05216535_3145 | Cytidylate kinase. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.866 |
cmk | nrdB | SAMN05216535_2084 | SAMN05216535_3146 | Cytidylate kinase. | Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.878 |
cmk | yqgE | SAMN05216535_2084 | SAMN05216535_0009 | Cytidylate kinase. | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. | 0.679 |