node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEH51445.1 | SEH72728.1 | SAMN05216535_0198 | SAMN05216535_1496 | ATP-dependent DNA helicase, RecQ-like. | DNA topoisomerase-3. | 0.986 |
SEH51445.1 | recJ | SAMN05216535_0198 | SAMN05216535_3239 | ATP-dependent DNA helicase, RecQ-like. | single-stranded-DNA-specific exonuclease. | 0.642 |
SEH51445.1 | ssb | SAMN05216535_0198 | SAMN05216535_0941 | ATP-dependent DNA helicase, RecQ-like. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.456 |
SEH51445.1 | topA | SAMN05216535_0198 | SAMN05216535_3010 | ATP-dependent DNA helicase, RecQ-like. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.982 |
SEH70349.1 | recJ | SAMN05216535_1352 | SAMN05216535_3239 | Exodeoxyribonuclease I subunit C. | single-stranded-DNA-specific exonuclease. | 0.703 |
SEH70349.1 | ssb | SAMN05216535_1352 | SAMN05216535_0941 | Exodeoxyribonuclease I subunit C. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.885 |
SEH72728.1 | SEH51445.1 | SAMN05216535_1496 | SAMN05216535_0198 | DNA topoisomerase-3. | ATP-dependent DNA helicase, RecQ-like. | 0.986 |
SEH72728.1 | recJ | SAMN05216535_1496 | SAMN05216535_3239 | DNA topoisomerase-3. | single-stranded-DNA-specific exonuclease. | 0.721 |
SEH72728.1 | ssb | SAMN05216535_1496 | SAMN05216535_0941 | DNA topoisomerase-3. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.669 |
dnaG | recJ | SAMN05216535_0833 | SAMN05216535_3239 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | single-stranded-DNA-specific exonuclease. | 0.605 |
dnaG | rluC | SAMN05216535_0833 | SAMN05216535_1707 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 23S rRNA pseudouridine955/2504/2580 synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.460 |
dnaG | ruvC | SAMN05216535_0833 | SAMN05216535_1763 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Holliday junction endonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.446 |
dnaG | ssb | SAMN05216535_0833 | SAMN05216535_0941 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.470 |
dnaG | topA | SAMN05216535_0833 | SAMN05216535_3010 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.604 |
mfd | murE | SAMN05216535_1679 | SAMN05216535_3614 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.442 |
mfd | recJ | SAMN05216535_1679 | SAMN05216535_3239 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | single-stranded-DNA-specific exonuclease. | 0.619 |
murE | mfd | SAMN05216535_3614 | SAMN05216535_1679 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.442 |
murE | recJ | SAMN05216535_3614 | SAMN05216535_3239 | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | single-stranded-DNA-specific exonuclease. | 0.556 |
recJ | SEH51445.1 | SAMN05216535_3239 | SAMN05216535_0198 | single-stranded-DNA-specific exonuclease. | ATP-dependent DNA helicase, RecQ-like. | 0.642 |
recJ | SEH70349.1 | SAMN05216535_3239 | SAMN05216535_1352 | single-stranded-DNA-specific exonuclease. | Exodeoxyribonuclease I subunit C. | 0.703 |