STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBGlutathione synthetase; Belongs to the prokaryotic GSH synthase family. (327 aa)    
Predicted Functional Partners:
gshA
Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
  
 
 0.962
pepA
Cytosol aminopeptidase PepA; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.926
gor
Glutathione reductase.
     
 0.921
pepD
Aminoacyl-histidine dipeptidase (Peptidase D).
     
 0.908
pepN
Membrane alanine aminopeptidase N.
    
 0.904
SAM56906.1
Glutathione S-transferase family protein.
     
  0.900
SAM56907.1
Glutathione S-transferase family protein.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.800
SAM62673.1
Hypothetical protein.
       0.773
grxD
Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
     0.601
Your Current Organism:
Cardiobacterium hominis
NCBI taxonomy Id: 2718
Other names: ATCC 15826, C. hominis, CCUG 2711, CIP 70.70, DSM 8339, LMG 3916, LMG:3916, NCTC 10426
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.