node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SAM65896.1 | guaA3 | CHUV0807_1423 | CHUV0807_1422 | Hypothetical protein. | GMP synthase. | 0.703 |
SAY96634.1 | apt | CHUV0807_1508 | CHUV0807_2045 | 5'(3')-deoxyribonucleotidase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
SAY96634.1 | gmk | CHUV0807_1508 | CHUV0807_0210 | 5'(3')-deoxyribonucleotidase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
SAY96634.1 | guaA | CHUV0807_1508 | CHUV0807_0996 | 5'(3')-deoxyribonucleotidase. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.900 |
SAY96634.1 | guaA-2 | CHUV0807_1508 | CHUV0807_1057 | 5'(3')-deoxyribonucleotidase. | Glutamine amidotransferase class-I. | 0.900 |
SAY96634.1 | guaA3 | CHUV0807_1508 | CHUV0807_1422 | 5'(3')-deoxyribonucleotidase. | GMP synthase. | 0.900 |
SAY96634.1 | guaB | CHUV0807_1508 | CHUV0807_1004 | 5'(3')-deoxyribonucleotidase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
SAY96634.1 | hpt | CHUV0807_1508 | CHUV0807_1294 | 5'(3')-deoxyribonucleotidase. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.922 |
SAY96634.1 | rdgB | CHUV0807_1508 | CHUV0807_1038 | 5'(3')-deoxyribonucleotidase. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
SAY96634.1 | surE | CHUV0807_1508 | CHUV0807_1992 | 5'(3')-deoxyribonucleotidase. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
apt | SAY96634.1 | CHUV0807_2045 | CHUV0807_1508 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'(3')-deoxyribonucleotidase. | 0.900 |
apt | gmk | CHUV0807_2045 | CHUV0807_0210 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.957 |
apt | guaA | CHUV0807_2045 | CHUV0807_0996 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.985 |
apt | guaA-2 | CHUV0807_2045 | CHUV0807_1057 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Glutamine amidotransferase class-I. | 0.921 |
apt | guaA3 | CHUV0807_2045 | CHUV0807_1422 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase. | 0.921 |
apt | guaB | CHUV0807_2045 | CHUV0807_1004 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.611 |
apt | hpt | CHUV0807_2045 | CHUV0807_1294 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.931 |
apt | surE | CHUV0807_2045 | CHUV0807_1992 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.914 |
gmk | SAY96634.1 | CHUV0807_0210 | CHUV0807_1508 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'(3')-deoxyribonucleotidase. | 0.900 |
gmk | apt | CHUV0807_0210 | CHUV0807_2045 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.957 |