node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SAM68397.1 | polA | CHUV0807_1918 | CHUV0807_0020 | Exonuclease SbcC. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.956 |
SAM68397.1 | recA | CHUV0807_1918 | CHUV0807_0814 | Exonuclease SbcC. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.663 |
SAM68397.1 | topA | CHUV0807_1918 | CHUV0807_1946 | Exonuclease SbcC. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.816 |
SAM68607.1 | SlyA_2 | CHUV0807_1948 | CHUV0807_1945 | Uncharacterized protein with LysM domain, COG1652. | Transcriptional regulator, MarR family. | 0.706 |
SAM68607.1 | dprA | CHUV0807_1948 | CHUV0807_1947 | Uncharacterized protein with LysM domain, COG1652. | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | 0.800 |
SAM68607.1 | topA | CHUV0807_1948 | CHUV0807_1946 | Uncharacterized protein with LysM domain, COG1652. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.778 |
SlyA_2 | SAM68607.1 | CHUV0807_1945 | CHUV0807_1948 | Transcriptional regulator, MarR family. | Uncharacterized protein with LysM domain, COG1652. | 0.706 |
SlyA_2 | dprA | CHUV0807_1945 | CHUV0807_1947 | Transcriptional regulator, MarR family. | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | 0.714 |
SlyA_2 | topA | CHUV0807_1945 | CHUV0807_1946 | Transcriptional regulator, MarR family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.805 |
dprA | SAM68607.1 | CHUV0807_1947 | CHUV0807_1948 | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | Uncharacterized protein with LysM domain, COG1652. | 0.800 |
dprA | SlyA_2 | CHUV0807_1947 | CHUV0807_1945 | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | Transcriptional regulator, MarR family. | 0.714 |
dprA | recA | CHUV0807_1947 | CHUV0807_0814 | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.524 |
dprA | topA | CHUV0807_1947 | CHUV0807_1946 | Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.971 |
leuS | polA | CHUV0807_0092 | CHUV0807_0020 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.616 |
leuS | recA | CHUV0807_0092 | CHUV0807_0814 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.419 |
leuS | rpoA | CHUV0807_0092 | CHUV0807_2092 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.531 |
leuS | rpoC | CHUV0807_0092 | CHUV0807_2066 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.419 |
leuS | topA | CHUV0807_0092 | CHUV0807_1946 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.764 |
pcrA | polA | CHUV0807_1114 | CHUV0807_0020 | ATP-dependent DNA helicase UvrD/PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.668 |
pcrA | recA | CHUV0807_1114 | CHUV0807_0814 | ATP-dependent DNA helicase UvrD/PcrA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.717 |