STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AFZ58327.1Phosphoenolpyruvate synthase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: phosphoenolpyruvate synthase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR002192:IPR008279:IPR000121; KEGG: naz:Aazo_1774 pyruvate, water dikinase; PFAM: PEP-utilising enzyme; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/pyruvate-binding; PRIAM: Pyruvate, water dikinase; SPTR: Pyruvate, water dikinase. (796 aa)    
Predicted Functional Partners:
AFZ56372.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
    
 0.952
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.934
AFZ57763.1
D-lactate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: npu:Npun_F2517 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: D-lactate dehydrogenase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
  
 0.931
AFZ59572.1
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
  
 
0.928
AFZ59816.1
PFAM: PEP-utilising enzyme, mobile domain; Domain of unknown function (DUF205); Pyruvate phosphate dikinase, PEP/pyruvate binding domain; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterPro IPR003811:IPR002192:IPR008279; KEGG: naz:Aazo_0133 pyruvate phosphate dikinase PEP/pyruvate-binding protein; PFAM: Pyruvate phosphate dikinase, PEP/pyruvate-binding; Glycerol-3-phosphate acyltransferase, bacteria; PEP-utilising enzyme, mobile domain; SPTR: Pyruvate phosphate dikinase PEP/pyruvate-binding protein.
  
  
 
0.925
AFZ56527.1
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: Malic enzyme, NAD binding domain; ACT domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012302:IPR002912:IPR012301; KEGG: naz:Aazo_1656 malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; Amino acid-binding ACT; PRIAM: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); SMART: Malic enzyme, NAD-binding; SPTR: Malate dehydrogenase (Oxaloacetate-decarboxylating).
  
 
 0.924
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.918
ppc
Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.915
AFZ56930.1
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.913
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: naz:Aazo_2767 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.841
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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