Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AFZ58615.1PFAM: Peptidase family M23; LysM domain; TIGRFAM: YD repeat (two copies); COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: naz:Aazo_4610 peptidase M23; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23. (778 aa)    
Predicted Functional Partners:
AFZ60803.1
PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; FHA domain; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR000253:IPR001264:IPR001460; KEGG: naz:Aazo_2326 FHA modulated glycosyl transferase/transpeptidase; PFAM: Glycosyl transferase, family 51; Forkhead-associated (FHA) domain; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SMART: Forkhead-associated (FHA) domain; SPTR: FHA modulated glycosyl transferase/transpeptidase.
 
  
 0.739
AFZ56164.1
PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: naz:Aazo_0862 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; PRIAM: N-acetylmuramoyl-L-alanine amidase; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase.
 
   
 0.680
AFZ60331.1
Hypothetical protein; PFAM: Carbohydrate binding domain; KEGG: mxa:MXAN_4606 carbohydrate-binding protein; SPTR: Carbohydrate-binding protein.
  
 
 0.677
AFZ57740.1
PFAM: Transglycosylase SLT domain; COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: naz:Aazo_2239 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Lytic transglycosylase catalytic.
 
  
 0.664
AFZ55927.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein 1B; penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816; KEGG: npu:Npun_R2017 1A family penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
 
  
 0.662
AFZ58444.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816; KEGG: naz:Aazo_2066 1A family penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
 
  
 0.657
AFZ59118.1
Cell wall hydrolase/autolysin; PFAM: Putative peptidoglycan binding domain; N-acetylmuramoyl-L-alanine amidase; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508:IPR002477; KEGG: naz:Aazo_3619 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan binding-like; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin.
 
   
 0.638
AFZ59628.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR003018:IPR000014:IPR 003661:IPR003594:IPR008207:IPR013767:IPR013955; KEGG: ava:Ava_0238 multi-component transcriptional regulator; PFAM [...]
  
 
 0.634
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
   
 0.630
AFZ59742.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264:IPR001460:IPR011816; KEGG: naz:Aazo_4703 1A family penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
 
  
 0.629
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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