STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ59712.1Twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593:IPR001482:IPR006321; KEGG: naz:Aazo_1969 twitching motility protein; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Twitching motility protein; TIGRFAM: Pilus retraction protein PilT. (374 aa)    
Predicted Functional Partners:
AFZ59711.1
PFAM: Bacterial type II secretion system protein F domain; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: naz:Aazo_1968 type II secretion system F domain-containing protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system F domain protein.
 
  
 0.921
AFZ57540.1
PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM; COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR003494:IPR005883; KEGG: naz:Aazo_0322 type IV pilus assembly protein PilM; SMART: Cell division protein FtsA domain; SPTR: Type IV pilus assembly protein PilM; TIGRFAM: Type IV pilus assembly protein PilM.
 
   
 0.844
AFZ57340.1
Type 4 prepilin peptidase 1; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.834
AFZ59713.1
PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR007831:IPR001482; KEGG: npu:Npun_R0118 type II secretion system protein E; PFAM: Type II secretion system protein E; General secretory system II, protein E, N-terminal; SPTR: Type II secretion system protein E.
 
  
0.723
AFZ56959.1
General secretion pathway protein H; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain; InterPro IPR012902; KEGG: npu:Npun_F0676 general secretion pathway protein H; SPTR: General secretion pathway protein H.
 
   
 0.609
AFZ59930.1
PFAM: Type II/IV secretion system protein; COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482:IPR003593; KEGG: gvi:gll0921 general secretion pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: Putative General secretion pathway protein E.
 
  
0.448
AFZ59710.1
KEGG: npu:Npun_R0115 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.432
AFZ58929.1
PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; COGs: COG0658 membrane metal-binding protein; InterPro IPR004477; KEGG: naz:Aazo_0924 comEC/Rec2-like protein; PFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein.
     
 0.429
AFZ59628.1
Multi-component transcriptional regulator, winged helix family; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR001867:IPR003018:IPR000014:IPR 003661:IPR003594:IPR008207:IPR013767:IPR013955; KEGG: ava:Ava_0238 multi-component transcriptional regulator; PFAM [...]
     
 0.425
AFZ60834.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: naz:Aazo_2338 GAF sensor-containing adenylate/guanylate cyclase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisati [...]
     
 0.422
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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