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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.920
AFZ58654.1
Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ava:Ava_2704 farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.915
AFZ59985.1
PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142:IPR004634:IPR004635; KEGG: naz:Aazo_4597 signal peptide peptidase SppA; PFAM: Peptidase S49; SPTR: Signal peptide peptidase SppA, 67K type; TIGRFAM: Peptidase S49, protease IV; Peptidase S49, SppA.
       0.608
AFZ57431.1
PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590:IPR005932; KEGG: naz:Aazo_3142 delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Proline dehydrogenase; SPTR: Delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 2; L-proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.458
AFZ56372.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
     
 0.428
AFZ56827.1
Long-chain-fatty-acid--(acyl-carrier-protein) ligase, 6-deoxyerythronolide-B synthase; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; KR domain; Beta-ketoacyl synthase, N-terminal domain; AMP-binding enzyme; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG3321 Polyketide synthase modules and related protein; InterProIPR020806:IPR020841:IPR020801:IPR020842:IPR 000873:IPR006163:IPR014030:IPR014031:IPR014043:IPR013968; KEGG: ava:Ava_3985 short-chain dehydrogenase/reductase SDR; PFAM: Beta-ketoacyl synthase, N- [...]
  
 
 0.425
AFZ59987.1
Outer membrane adhesin like proteiin; PFAM: Calx-beta domain; Bacterial pre-peptidase C-terminal domain; InterPro IPR003644:IPR007280:IPR010221; KEGG: mar:MAE_12400 putative peptidase; PFAM: Na-Ca exchanger/integrin-beta4; Peptidase, C-terminal, archaeal/bacterial; SMART: Na-Ca exchanger/integrin-beta4; SPTR: Putative uncharacterized protein; TIGRFAM: VCBS repeat.
       0.417
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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