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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ60137.1PFAM: Pentapeptide repeats (8 copies); COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: npu:Npun_F0979 pentapeptide repeat-containing protein; PFAM: Pentapeptide repeat; SPTR: Pentapeptide repeat protein. (519 aa)    
Predicted Functional Partners:
AFZ60136.1
Arogenate dehydrogenase (NADP); PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: naz:Aazo_3900 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase.
       0.558
AFZ60834.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: naz:Aazo_2338 GAF sensor-containing adenylate/guanylate cyclase; PFAM: ATPase-like, ATP-binding domain; GAF; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisati [...]
  
 
   0.518
Your Current Organism:
Anabaena cylindrica
NCBI taxonomy Id: 272123
Other names: A. cylindrica PCC 7122, Anabaena cylindrica IAM M-1, Anabaena cylindrica NIES-19, Anabaena cylindrica PCC 7122, Anabaena cylindrica UTEX B 629, Anabaena sp. ATCC 27899, Anabaena sp. PCC 7122
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