Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
APE_0055Conserved hypothetical protein. (430 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
    0.631
APE_0056.1
enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
    0.582
APE_0010.1
Putative amino acid transporter.
  
  
 0.576
APE_0054.1
Hypothetical protein.
       0.548
APE_0060.1
Conserved hypothetical protein.
 
     0.506
APE_0972.1
Sodium/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.501
APE_2154.1
Twin-arginine translocation protein, TatC.
     
 0.463
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
    0.447
APE_0140.1
ATP-dependent universal stress protein.
 
   
 0.438
APE_0053.1
Fumarylacetoacetate hydrolase family protein.
  
    0.421
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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