Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mclmalyl-CoA lyase. (276 aa)    
Predicted Functional Partners:
APE_1657.1
Aldolase class II protein.
  
  
 0.871
fadD
long-chain-fatty-acid--CoA ligase.
    
 0.815
citG
2-(5'-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase.
  
  
 0.771
APE_1876
Hypothetical protein.
  
  
 0.771
APE_0306.1
Putative carbohydrate kinase.
  
  
 0.597
sdhA
Succinate dehydrogenase subunit A.
  
  
 0.576
APE_0313.1
Conserved hypothetical protein.
       0.516
prpD
2-methylcitrate dehydratase.
  
  
 0.516
APE_0392
Malate dehydrogenase; Malic enzyme.
  
  
 0.510
htpX
Zinc metalloprotease HtpX; Belongs to the peptidase M48B family.
  
  
 0.510
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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