STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APE_0641Thioredoxin; ApTrx. (349 aa)    
Predicted Functional Partners:
APE_2278
Thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.939
APE_1061.1
Thioredoxin reductase; ApTR.
  
 
 0.886
tuf
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
    
 
 0.835
APE_2151.1
Serine protease.
     
 0.788
APE_1458
Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.625
pdhD
Dihydrolipoyl dehydrogenase; Glycine cleavage system L protein; pyruvate dehydrogenase complex, E3 component.
  
 0.625
APE_2062.1
Ribonucleotide reductase, B12-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.598
APE_2274
Putative cytochrome C-type biogenesis protein.
  
  
 0.559
APE_0072
Heme exporter protein C.
  
  
 0.545
APE_0791.1
Putative ATP/GTP-binding protein.
   
 0.520
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.