node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE_0446 | priA | APE_0446 | APE_0438.1 | Conserved hypothetical protein. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.432 |
APE_0446 | rps8e | APE_0446 | APE_0789 | Conserved hypothetical protein. | 30S ribosomal protein S8e. | 0.418 |
APE_0446 | top6A | APE_0446 | APE_0703.1 | Conserved hypothetical protein. | Type II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.466 |
APE_0446 | top6B | APE_0446 | APE_0706.1 | Conserved hypothetical protein. | Type II DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.541 |
APE_0932.1 | APE_1436.1 | APE_0932.1 | APE_1436.1 | Conserved hypothetical protein. | Repair endonuclease XPF. | 0.785 |
APE_0932.1 | rnhB | APE_0932.1 | APE_0496.1 | Conserved hypothetical protein. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.818 |
APE_0932.1 | top6B | APE_0932.1 | APE_0706.1 | Conserved hypothetical protein. | Type II DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.787 |
APE_1436.1 | APE_0932.1 | APE_1436.1 | APE_0932.1 | Repair endonuclease XPF. | Conserved hypothetical protein. | 0.785 |
APE_1436.1 | rnhB | APE_1436.1 | APE_0496.1 | Repair endonuclease XPF. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.861 |
APE_1436.1 | top6A | APE_1436.1 | APE_0703.1 | Repair endonuclease XPF. | Type II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.617 |
APE_1436.1 | top6B | APE_1436.1 | APE_0706.1 | Repair endonuclease XPF. | Type II DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.785 |
dnaG | orc1 | APE_2096.1 | APE_0475.1 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Origin recognition complex subunit 1 Orc1; Involved in regulation of DNA replication (By similarity). Binds DNA; Belongs to the CDC6/cdc18 family. | 0.731 |
dnaG | priA | APE_2096.1 | APE_0438.1 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.835 |
dnaG | rnhB | APE_2096.1 | APE_0496.1 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.487 |
dnaG | rps8e | APE_2096.1 | APE_0789 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 30S ribosomal protein S8e. | 0.426 |
dnaG | top6A | APE_2096.1 | APE_0703.1 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Type II DNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.878 |
dnaG | top6B | APE_2096.1 | APE_0706.1 | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | Type II DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.583 |
dtdA | rps8e | APE_1483.1 | APE_0789 | Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. | 30S ribosomal protein S8e. | 0.494 |
dtdA | top6B | APE_1483.1 | APE_0706.1 | Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. | Type II DNA topoisomerase VI subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.495 |
orc1 | dnaG | APE_0475.1 | APE_2096.1 | Origin recognition complex subunit 1 Orc1; Involved in regulation of DNA replication (By similarity). Binds DNA; Belongs to the CDC6/cdc18 family. | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.731 |