Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
APE_0777Serine/threonine protein phosphatase. (266 aa)    
Predicted Functional Partners:
APE_0791.1
Putative ATP/GTP-binding protein.
  
 0.908
APE_0326.1
TATA box-binding protein-interacting protein TIP49.
  
 
 
 0.784
APE_2361.1
Putative hydrolase.
   
 0.771
APE_0181
Putative exonuclease.
   
 0.706
APE_2295.1
Conserved hypothetical protein.
   
 0.706
APE_0413
Conserved hypothetical protein.
   
 0.704
rpl30e
50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family.
  
 
  0.687
rpl3p
50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
  0.654
psmA
Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 0.642
APE_0540.1
Conserved hypothetical protein.
  
  
  0.635
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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