Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (187 aa)    
Predicted Functional Partners:
rfbD
dTDP-4-dehydrorhamnose reductase; RmlD.
 
 0.999
rfbB
dTDP-glucose 4,6-dehydratase; RmlB.
 
 
 0.999
rfbA
Glucose-1-phosphate thymidylyltransferase; RmlA; dTDP-glucose synthase.
 
  
 0.993
APE_1184
Glycosyl transferase, family 2.
 
  
 0.757
APE_0255.1
Putative sugar-phosphate nucleotidyl transferase.
  
  
 0.703
APE_2291
Putative sugar-phosphate nucleotidyl transferase.
  
  
 0.703
APE_1202.1
Putative nucleotidyl transferase.
  
  
 0.693
APE_1208.1
Putative nucleotidyl transferase.
  
  
 0.693
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
     
 0.633
APE_1186.1
Hypothetical protein.
  
  
 0.628
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.