node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE_0754.1 | APE_2199.1 | APE_0754.1 | APE_2199.1 | Conserved hypothetical protein. | snoRNA binding protein; aNOP56. | 0.988 |
APE_0754.1 | csl4 | APE_0754.1 | APE_0445 | Conserved hypothetical protein. | Exosome complex RNA-binding protein Cs14 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.964 |
APE_0754.1 | dnaG | APE_0754.1 | APE_2096.1 | Conserved hypothetical protein. | Exosome complex RNA helicase DnaG homologue; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.551 |
APE_0754.1 | nep1 | APE_0754.1 | APE_0502 | Conserved hypothetical protein. | Ribosome biogenesis protein NEP1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
APE_0754.1 | rps4p | APE_0754.1 | APE_1739.1 | Conserved hypothetical protein. | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.996 |
APE_0754.1 | rrp4 | APE_0754.1 | APE_1448 | Conserved hypothetical protein. | Exosome complex RNA-binding protein Rrp4 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.947 |
APE_0754.1 | rrp41 | APE_0754.1 | APE_1447 | Conserved hypothetical protein. | Exosome complex exonuclease Rrp41 homologue; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.881 |
APE_0754.1 | rrp42 | APE_0754.1 | APE_1445 | Conserved hypothetical protein. | Exosome complex exonuclease Rrp42 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.930 |
APE_0754.1 | rtcA | APE_0754.1 | APE_0511.1 | Conserved hypothetical protein. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.960 |
APE_2199.1 | APE_0754.1 | APE_2199.1 | APE_0754.1 | snoRNA binding protein; aNOP56. | Conserved hypothetical protein. | 0.988 |
APE_2199.1 | csl4 | APE_2199.1 | APE_0445 | snoRNA binding protein; aNOP56. | Exosome complex RNA-binding protein Cs14 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | 0.932 |
APE_2199.1 | nep1 | APE_2199.1 | APE_0502 | snoRNA binding protein; aNOP56. | Ribosome biogenesis protein NEP1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. | 0.999 |
APE_2199.1 | rpl37ae | APE_2199.1 | APE_1443a | snoRNA binding protein; aNOP56. | 50S ribosomal protein L37Ae; Binds to the 23S rRNA. | 0.447 |
APE_2199.1 | rps4p | APE_2199.1 | APE_1739.1 | snoRNA binding protein; aNOP56. | 30S ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.978 |
APE_2199.1 | rrp4 | APE_2199.1 | APE_1448 | snoRNA binding protein; aNOP56. | Exosome complex RNA-binding protein Rrp4 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. | 0.902 |
APE_2199.1 | rrp41 | APE_2199.1 | APE_1447 | snoRNA binding protein; aNOP56. | Exosome complex exonuclease Rrp41 homologue; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. | 0.826 |
APE_2199.1 | rrp42 | APE_2199.1 | APE_1445 | snoRNA binding protein; aNOP56. | Exosome complex exonuclease Rrp42 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.894 |
APE_2199.1 | rtcA | APE_2199.1 | APE_0511.1 | snoRNA binding protein; aNOP56. | RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity). | 0.975 |
csl4 | APE_0754.1 | APE_0445 | APE_0754.1 | Exosome complex RNA-binding protein Cs14 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | Conserved hypothetical protein. | 0.964 |
csl4 | APE_2199.1 | APE_0445 | APE_2199.1 | Exosome complex RNA-binding protein Cs14 homologue; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. | snoRNA binding protein; aNOP56. | 0.932 |