Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
APE_1457Conserved hypothetical protein; Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction. Belongs to the Dps family. (173 aa)    
Predicted Functional Partners:
APE_0203.1
Conserved hypothetical protein.
 
    0.601
APE_1458
Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
       0.510
APE_0798
Hypothetical protein.
   
    0.473
APE_2021.1
Putative transcriptional regulator, Fur family.
 
     0.449
APE_1779.1
Conserved hypothetical protein.
  
    0.412
APE_2556.1
Probable arsenite oxidase large subunit.
  
     0.412
APE_1297
Putative nitrate reductase, gamma subunit.
  
     0.409
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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