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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
ino1Inositol-3-phosphate synthase. (392 aa)    
Predicted Functional Partners:
APE_1516.1
Putative CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.985
APE_1514.1
Hypothetical protein.
    
 0.969
fbpA-2
Fructose-1,6-bisphosphatase; FBPase; Belongs to the inositol monophosphatase superfamily.
  
 
 0.943
APE_0317.1
Phospho-sugar mutase; Belongs to the phosphohexose mutase family.
    
 0.904
glk
ATP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ATP as the phosphate donor. ITP can also serve as an effective phosphoryl donor. According to Hansen et al., the enzyme has a broad hexose specificity, and in addition to glucose, which shows the highest catalytic efficiency, it can also phosphorylate fructose, mannose, glucosamine, N-acetylglucosamine, N- acetylmannosamine and 2-deoxyglucose. However, according to Sakuraba et al., the enzyme shows strict specificity for D-glucose.
     
 0.900
APE_1073
Putative DNA repair helicase.
    
   0.779
APE_1526.1
Putative CDP-alcohol phosphatidyltransferase; Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn- glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3- phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
 
   
 0.752
APE_2254.1
Probable ABC transporter, substrate binding protein.
 
     0.598
APE_1512
Conserved hypothetical protein; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
     0.555
APE_1630.1
ABC transporter, substrate binding protein.
 
     0.444
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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